Journal: eLife
Article Title: Gut microbe-derived trimethylamine shapes circadian rhythms through the host receptor TAAR5
doi: 10.7554/eLife.107037
Figure Lengend Snippet: Male or female wild-type mice ( Taar5 +/+ ) or mice lacking the TMA receptor ( Taar5 -/ ) were subjected to a battery of behavioral tests related to cognition, depression, and anxiety including: ( A ) cued fear conditioning, ( B ) elevated plus maze, ( C ) Y-maze, and ( D ) open field test as described in the Methods section. Data are shown for the entire cohort combining both sexes or divided into either male or female cohorts to examine sexual dimorphism in phenotype. Data represent the mean ± SEM from n = 9–10 per group when male and female are separated ( n = 19–20 when both sexes are combined). Significant differences between Taar5 +/+ and Taar5 -/- mice were determined by Student’s t -tests (*p < 0.05).
Article Snippet: Other , Fear Conditioning Chambers , Med Associates , #VFC-008 , Behavioral testing.
Techniques: Battery